A question about COM ports

Hi

In my 6 DOF race simulator, I’m planning tu use 3 ODrives, I’ve bought a PCI usb expansion card like this:

I’m using this software:

Now I was wondering if it is necessary to plug the Odrives into the same USB port every time, or is there anything else that I need to do, to get the system woking the right way? For example a program that links the right COM port automatically. (I dont know if a COM port is something hardware or software)

(feel free to ask questions)

Thanks in advance

Cheers

Carelsbergh Stijn