Odrive can't boot with startup

at my last topic RPI 4B USB communication issue
I find RPi can’t boot with odrive, and I use an isolator to deal it.
But i meet an other problem that my odrive can’t boot sometimes.
At first time, I consider there were something wrong with my usb line.
Then I found the reason was odrive not boot normaly because the startup I set was not worked.
When I powered odrive, half the time odrive doesn’t work on usb and startup.